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Multidisciplinary Biomechanical Characterization of Non-Pathologic Subsynovial Connective Tissue—University of Iowa OVPR Biological Sciences Funding Program
04/15/09–06/30/10
Jessica E. Goetz, Ph.D., Principal Investigator
Thomas E. Baer, B.A., Mechanical Designer/Machinist
Gail L. Kurriger, B.S., H.T. (ASCP), Histology Technician
Thomas D. Brown, Ph.D., Ericka A. Lawler, M.D., Yuki Tochigi, M.D., Ph.D., Consultants

 

Risks and Benefits of Antioxidant Therapy for Post-Traumatic Arthritis—Department of Veterans Affairs

Research  
Research  
 
 

Orthopaedic Biomechanics
Laboratory Home
Page

04/01/09–03/31/12

Joseph A. Buckwalter, M.D., Principal Investigator

James A. Martin, Ph.D., Lei Ding, Ph.D., Prem S. Ramkrishnan, Ph.D.,
Yuki Tochigi, Ph.D., Co-Investigators

 

Acute Cartilage Damage Associated with Intraarticular Fractures— Orthopaedic Trauma Association

01/01/09–12/31/09

Yuki Tochigi, M.D., Ph.D., Principal Investigator

Todd O. McKinley, M.D., Co-Principal Investigator

James A. Martin, Ph.D., M. James Rudert, Ph.D., Investigators

 

Quantification of Functional Limitation in Older Adults with Symptomatic Knee Osteoarthritis Through Evaluation of Gait Variability—Foundation for Physical Medicine & Rehabilitation
10/01/08–09/30/10
Neil A. Segal, M.D., Principal Investigator
Yuki Tochigi, M.D., Ph.D., Co-Investigator

 

Quantifying Fracture Severity Using a 3-D Puzzle Solving Approach—
NIH 1 R21 AR054015

07/01/2008–03/31/2010
Donald D. Anderson, Ph.D., Principal Investigator
J. Lawrence Marsh, M.D., Thomas D. Brown, Ph.D., Co-Investigators

Andrew R. Willis, Ph.D., Principal Investigator on subaward to the University of North Carolina at Charlotte
 

Objective Assessment of Fracture-Associated Soft Tissue Injury Using CT-Based Texture Analysis—Orthopaedic Trauma Association
01/01/2008–06/30/2009
Donald D. Anderson, Ph.D., J. Lawrence Marsh, M.D., Principal Investigators

Thomas D. Brown, Ph.D., Investigator

Biomechanics of Total Hip Impingement & Dislocation—Department of Veterans Affairs

10/01/2007–09/30/2011
John J. Callaghan, M.D., Principal Investigator
Thomas D. Brown, Ph.D., H. John Yack, Ph.D., Co-Investigators
Thomas E. Baer, B.A., Douglas R. Pedersen, Ph.D., Investigator
 

New Approaches to Assess and Forestall Osteoarthritis in Injured Joints—NIH 5 P50 AR055533
09/10/2007–08/31/2012
Joseph A. Buckwalter, M.D., CORT Director
Thomas D. Brown, Ph.D., CORT Associate Director

Project 1: Cartilage Extracellular Matrix Fragments and Trauma-Induced Chondrolysis
Joseph A. Buckwalter, M.D., Principal Investigator
James A. Martin, Ph.D., Co-Principal Investigator
Gene A. Homandberg, Ph.D., Prem Ramakrishnan, Ph.D., Honjun Zheng, Ph.D., Investigators

Project 2: Acute Versus Chronic Mechanical Damage in the Etiology of Post-Traumatic OA
Todd O. McKinley, M.D., Principal Investigator
James A. Martin, Ph.D., M. James Rudert, Ph.D.,
Yuki Tochigi, M.D., Ph.D., Investigators

Project 3: Validation and Application of MRI Biomarkers in Assessing Articular Cartilage Health
Douglas R. Pedersen, Ph.D., Principal Investigator
Annunziato Amendola, M.D., Co-Principal Investigator
James A. Martin, Ph.D., Daniel R. Thedens, Ph.D.,
Glenn Williams, Ph.D., Investigators

 

Project 4: Quantifying Injury Severity to Assess the Risk for Post-Traumatic Osteoarthritis
J. Lawrence Marsh, M.D., Principal Investigator
Donald D. Anderson, Ph.D., Co-Principal Investigator

Administrative Core
Joseph A. Buckwalter, M.D., Director
Thomas D. Brown, Ph.D., Associate Director
Martha L. Gray, Ph.D., Walter Herzog, Ph.D.,
Jack L. Lewis, Ph.D., Stefan Lohmander, M.D., Ph.D.,
Carol Vonwald, R.N., Advisory Group
Stephen L. Hillis, Ph.D., Biostatistician
Lois A. Lembke, M.S., Grant Administrator

Biomechanics & Imaging Core
Thomas D. Brown, Ph.D., Principal Investigator
Thomas E. Baer, B.A., George Y. El-Khoury, M.D.,
Anneliese D. Heiner, Ph.D., M. James Rudert, Ph.D.,
Andrew R. Willis, Ph.D., Investigators

Tissue and Experimental Modeling Core
Yuki Tochigi, M.D., Ph.D., Principal Investigator
Douglas C. Fredericks, B.S., James A. Martin, Ph.D.,
M. James Rudert, Ph.D., Investigators
Annunziato Amendola, M.D., Thomas D. Brown, Ph.D.,
Michael G. Conzemius, D.V.M, Ph.D., Diplomate, A.C.V.S., Consultants

Local Biomechanics of Median Nerve Insult in Carpal Tunnel—
NIH 5 R01 AR053899

09/07/2007–08/31/2011
Thomas D. Brown, Ph.D, Principal Investigator
Ericka A. Lawler, M.D., M. James Rudert, Ph.D., Daniel R. Thedens, Ph.D.,
Yuki Tochigi, M.D., Ph.D., Co-Investigators

 

Biomechanics of the Dysplastic Hip—NIH 5 R01 AR053344 
07/01/2007–06/30/2012
Jeffrey A. Weiss, Ph.D., Principal Investigator
Christopher L. Peters, M.D., Co-Principal Investigator
Gerard Ateshian, Ph.D., Consultant
Thomas D. Brown, Ph.D., Subaward Principal Investigator
M. James Rudert, Ph.D., Thomas E. Baer, B.A., Subaward Investigators

 

Non-Invasive Assessment of Cartilage Health: A New Approach to T1-rho MRI—American Orthopaedic Society for Sports Medicine
04/01/2007–03/31/2009
Annunziato Amendola, M.D., Principal Investigator
Daniel R. Thedens, Ph.D., James A. Martin, Ph.D.,
Douglas R. Pedersen, Ph.D., Investigators

 

Three Dimensional Virtual Orthopaedic Reconstruction of Comminuted Fractures—University of Iowa Roy J. and Lucille A. Carver College of Medicine Roy J. Carver Charitable Trust Medical Research Initiative
02/01/200703/31/2009
Thomas D. Brown, Ph.D., Principal Investigator
Donald D. Anderson, Ph.D., Co-Investigator
Andrew R. Willis, Ph.D., Consultant

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Implant/Construct Interactions in the Biomechanics of Total Hip Dislocation—NIH 5 R01 AR053553

09/25/2006–08/31/2010

Thomas D. Brown, Ph.D., Principal Investigator

John J. Callaghan, M.D.,  Co-Investigator

Jeffrey A. Weiss, Ph.D., University of Utah, Co-Investigator

Douglas R. Pedersen, Ph.D., M. James Rudert, Ph.D.,

Yuki Tochigi, M.D., Ph.D., Investigators

 

Wear Analysis of Intervertebral Total Disc Replacements
NIH
5 R01 AR052653
10/01/2005–06/30/2010  
Thomas D. Brown, Ph.D., Principal Investigator
Richard M. Hall, Ph.D., John Fisher, Ph.D., Eileen Ingham, Ph.D.,
Heinz-Michael Mayer, M.D., Ph.D., Sergio A. Mendoza, M.D.,
Douglas R. Pedersen, Ph.D., Co-Investigators

 

KMI Universal Total Wrist Implant—Kinetikos Medical, Incorporated
03/31/1999–01/21/2009
Brian D. Adams, M.D., Principal Investigator

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  Department of Orthopaedics & Rehabilitation