researchgrants





		Risks and Benefits of Antioxidant Therapy for Post-Traumatic Arthritis—Department of Veterans Affairs 10/01/08–09/30/11 Joseph A. Buckwalter, M.D., Principal Investigator James A. Martin, Ph.D., Lei Ding, Ph.D., Prem S. Ramkrishnan, Ph.D. Yuki Tochigi, Ph.D., Co-Investigators Quantifying Fracture Severity Using a 3-D Puzzle Solving Approach— NIH 1 R21 AR054015 07/01/2008–03/31/2010 Donald D. Anderson, Ph.D., Principal Investigator J. Lawrence Marsh, M.D., Thomas D. Brown, Ph.D., Co-Investigators





Orthopaedic Biomechanics Laboratory Home Page		Andrew R. Willis, Ph.D., Principal Investigator on subaward to the University of North Carolina at Charlotte Objective Assessment of Fracture-Associated Soft Tissue Injury Using CT-Based Texture Analysis—Orthopaedic Trauma Association 01/01/2008–03/31/2009 Donald D. Anderson, Ph.D., J. Lawrence Marsh, M.D., Principal Investigators Thomas D. Brown, Ph.D., Investigator Biomechanics of Total Hip Impingement & Dislocation—Department of Veterans Affairs 10/01/2007–09/30/2011 John J. Callaghan, M.D., Principal Investigator Thomas D. Brown, Ph.D., H. John Yack, Ph.D., Co-Investigators Thomas E. Baer, B.A., Douglas R. Pedersen, Ph.D., Investigator New Approaches to Assess and Forestall Osteoarthritis in Injured Joints—NIH 5 P50 AR055533 09/10/2007–08/31/2012 Joseph A. Buckwalter, M.D., CORT Director Thomas D. Brown, Ph.D., CORT Associate Director Project 1: Cartilage Extracellular Matrix Fragments and Trauma-Induced Chondrolysis Joseph A. Buckwalter, M.D., Principal Investigator James A. Martin, Ph.D., Co-Principal Investigator Gene A. Homandberg, Ph.D., Prem Ramakrishnan, Ph.D., Honjun Zheng, Ph.D., Investigators Project 2: Acute Versus Chronic Mechanical Damage in the Etiology of Post-Traumatic OA Todd O. McKinley, M.D., Principal Investigator James A. Martin, Ph.D., M. James Rudert, Ph.D., Yuki Tochigi, M.D., Ph.D., Investigators Project 3: Validation and Application of MRI Biomarkers in Assessing Articular Cartilage Health Douglas R. Pedersen, Ph.D., Principal Investigator Annunziato Amendola, M.D., Co-Principal Investigator James A. Martin, Ph.D., Daniel R. Thedens, Ph.D., Glenn Williams, Ph.D., Investigators Project 4: Quantifying Injury Severity to Assess the Risk for Post-Traumatic Osteoarthritis J. Lawrence Marsh, M.D., Principal Investigator Donald D. Anderson, Ph.D., Co-Principal Investigator Administrative Core Joseph A. Buckwalter, M.D., Director Thomas D. Brown, Ph.D., Associate Director Martha L. Gray, Ph.D., Walter Herzog, Ph.D., Jack L. Lewis, Ph.D., Stefan Lohmander, M.D., Ph.D., Carol Vonwald, R.N., Advisory Group Stephen L. Hillis, Ph.D., Biostatistician Lois A. Lembke, M.S., Grant Administrator Biomechanics & Imaging Core Thomas D. Brown, Ph.D., Principal Investigator Thomas E. Baer, B.A., George Y. El-Khoury, M.D., Anneliese D. Heiner, Ph.D., M. James Rudert, Ph.D., Andrew R. Willis, Ph.D., Investigators Tissue and Experimental Modeling Core Yuki Tochigi, M.D., Ph.D., Principal Investigator Douglas C. Fredericks, B.S., James A. Martin, Ph.D., M. James Rudert, Ph.D., Investigators Annunziato Amendola, M.D., Thomas D. Brown, Ph.D., Michael G. Conzemius, D.V.M, Ph.D., Diplomate, A.C.V.S., Consultants Local Biomechanics of Median Nerve Insult in Carpal Tunnel—NIH 09/07/2007–08/31/2011 Thomas D. Brown, Ph.D, Principal Investigator Ericka A. Lawler, M.D., M. James Rudert, Ph.D., Daniel R. Thedens, Ph.D., Yuki Tochigi, M.D., Ph.D., Co-Investigators Biomechanics of the Dysplastic Hip—NIH 07/01/2007–06/30/2012 Jeffrey A. Weiss, Ph.D., Principal Investigator Christopher L. Peters, M.D., Co-Principal Investigator Gerard Ateshian, Ph.D., Consultant Thomas D. Brown, Ph.D., Subaward Principal Investigator M. James Rudert, Ph.D., Thomas E. Baer, B.A., Subaward Investigators Non-Invasive Assessment of Cartilage Health: A New Approach to T1-rho MRI—American Orthopaedic Society for Sports Medicine 04/01/2007–03/31/2009 Annunziato Amendola, M.D., Principal Investigator Daniel R. Thedens, Ph.D., James A. Martin, Ph.D., Douglas R. Pedersen, Ph.D., Investigators Three Dimensional Virtual Orthopaedic Reconstruction of Comminuted Fractures—University of Iowa Roy J. and Lucille A. Carver College of Medicine Roy J. Carver Charitable Trust Medical Research Initiative 02/01/2007–03/31/2009 Thomas D. Brown, Ph.D., Principal Investigator Donald D. Anderson, Ph.D., Co-Investigator Andrew R. Willis, Ph.D., Consultant Articular Contact: Identifying Patients At Risk For Painful Knee Osteoarthritis—University of Iowa OVPR Biological Sciences Funding Program 02/01/2007–08/31/2008 Neil A. Segal, M.D., Principal Investigator Donald D. Anderson, Ph.D., Co-Investigator Morgan Brubaker, Research Assistant Stephen L. Hillis, Ph.D., Consultant

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		Development of an Animal Model of Human Intra-Articular Fracture—University of Iowa OVPR Biological Sciences Funding Program 02/01/2007–12/31/2008 Yuki Tochigi, Ph.D., Principal Investigator James A. Martin, Ph.D., M. James Rudert, Ph.D., Investigators Thomas D. Brown, Ph.D., Michael G. Conzemius, D.V.M., Ph.D., Diplomate A.C.V.S., Todd O. McKinley, M.D., Consultants The Effects of Osteochondral Defects and Focal Resurfacing on Joint Contact Mechanics—Arthrosurface, Inc. 01/01/2007–12/31/2008 Annunziato Amendola, M.D., Principal Investigator Donald D. Anderson, Ph.D., Yuki Tochigi, M.D., Ph.D., Co-Principal Investigators Thomas D. Brown, Ph.D., Douglas R. Pedersen, Ph.D., M. James Rudert, Ph.D., Co-Investigators Thomas E. Baer, B.A., Research Associate Quantifying Intra-articular Fracture Severity as a Risk Factorfor Post-traumatic Osteoarthritis—World Arthrosis Organization 01/01/07–12/31/08 J. Lawrence Marsh, M.D., Principal Investigator Donald D. Anderson, Ph.D., Co-Principal Investigator Joseph A. Buckwalter, M.D., Investigator Implant/Construct Interactions in the Biomechanics of Total Hip Dislocation—NIH 09/25/2006–08/31/2010 Thomas D. Brown, Ph.D., Principal Investigator John J. Callaghan, M.D., Co-Investigator Jeffrey A. Weiss, Ph.D., University of Utah, Co-Investigator Douglas R. Pedersen, Ph.D., M. James Rudert, Ph.D., Yuki Tochigi, M.D., Ph.D., Investigators Wear Analysis of Intervertebral Total Disc Replacements—NIH 10/01/2005–06/30/2010 Thomas D. Brown, Ph.D., Principal Investigator Richard M. Hall, Ph.D., John Fisher, Ph.D., Eileen Ingham, Ph.D., Heinz-Michael Mayer, M.D., Ph.D., Sergio A. Mendoza, M.D., Douglas R. Pedersen, Ph.D., Co-Investigators Pathogenesis–Prevention of Post-Traumatic OA—NIH 09/16/2002–08/31/2008 Joseph A. Buckwalter, M.D., SCOR Director Thomas D. Brown, Ph.D., SCOR Co-Director Project 1: Mechanical Determinants of Post-Traumatic OA 09/16/2002–08/31/2008 J.L. Marsh, M.D., Principal Investigator Donald D. Anderson, Ph.D., Thomas D. Brown, Ph.D., George El-Khoury, M.D., Steven L. Hillis, Ph.D., Todd O. McKinley, M.D., Douglas R. Pedersen, Ph.D., Investigators Joseph A. Buckwalter, M.D., Charles L. Saltzman, M.D., Consultants Project 2: Effects of Distraction and Motion on Osteoarthritis 09/16/2002–08/31/2008 Annunziato Amendola M.D., Principal Investigator Thomas D. Brown, Ph.D., George El-Khoury, M.D., Steven L. Hillis, Ph.D., James A. Martin, Ph.D., M. James Rudert, Ph.D., Alan L. Stolpen, M.D., Ph.D., Daniel R. Thedens, Ph.D., Investigators Project 4: Oxidative Stress in Post-Traumatic OA 09/16/2002–08/31/2008 Joseph A. Buckwalter, M.D., Principal Investigator Anneliese D. Heiner, Ph.D., James A. Martin, Ph.D., Investigators Aloysius J. Klingelhutz, Ph.D., Collaborator Garry R. Buettner, Ph.D., Herbert Dircks, Consultants Administrative and Biostatistics Core 09/16/2002–08/31/2008 Joseph A. Buckwalter, M.D., Principal Investigator Stephen L. Hillis, Ph.D., Investigator Lois A. Lembke, M.S., Grant Administrator Biomechanics Core 09/16/2002–08/31/2008 Thomas D. Brown, Ph.D., Principal Investigator Donald D. Anderson, Ph.D., Investigator Douglas R. Pedersen, Ph.D., Investigator M. James Rudert, Ph.D., Investigator KMI Universal Total Wrist Implant—Kinetikos Medical, Incorporated 03/31/1999–01/21/2009 Brian D. Adams, M.D., Principal Investigator

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