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Anderson DD, Iyer KS, Segal NA, Lynch JA, Sharma L, Brown TD. Implementation of discrete element analysis for subject-specific, population-wide investigations of habitual contact stress exposure. J. Appl. Biomech. 2010;2:215223. PMC2905528.


Anderson DD, Tochigi Y, Rudert MJ, Vaseenon T, Brown TD, Amendola A. Effect of implantation accuracy on ankle contact mechanics with a metallic

focal resurfacing implant. J. Bone Joint Surg. Am. 2010;92:1490–1500. PMC2874671.


Anderson DD, Van Hofwegen C, Marsh JL, Brown TD. Is elevated contact stress predictive of post-traumatic osteoarthritis for imprecisely reduced tibial


Orthopaedic Biomechanics Laboratory Home Page


plafond fractures? J. Orthop. Res. 2011 ;29(1):33–39. PMC2972368.


Anderson DD, Chubinskaya S, Guilak F, Martin JA, Oegema TR, Olson SA, Buckwalter JA. Research Perspective – Post-traumatic osteoarthritis: Improved understanding and opportunities for early intervention. J Orthop. Res. 2011;29:802–809. PMC3082940.

Anderson DD, Marsh JL, Brown TD. OREF 2011 Clinical Research Award: The pathomechanical etiology of post-traumatic osteoarthritis following intra-articular fractures. Iowa Orthop. J. 2011;31:120.

Anderson DD, Marsh JL, Brown TD.  OREF 2011 Clinical Research Award: The pathomechanical etiology of post-traumatic osteoarthritis following intra-articular fractures. J. Am. Acad. Orthop. Surg. 2011;31:1-20. PMC3215107.


Beaule PE, Kim YJ, Rakhra KS, Stelzeneder D, Brown TD.  New Frontiers in Cartilage Imaging of the Hip.  2012 AAOS Instructional Course Lectures, Volume 61 (pp. 253-262).  Rosemont, IL:  American Academy of Orthopaedic Surgeons.


Callaghan JJ, Hennessy DW, Liu SS, Goetz KE, Heiner ADCementation of acetabular liners into secure cementless shells for cases of polyethylene wear.  Clinical Orthopaedics and Related Research (accepted)


Debevec H, Pedersen DR, Iglie A, Daniel M. One-legged stance as a representative static body position for calculation of hip contact stress distribution in clinical studies. J. Appl. Biomech. 2010 26(4):522–525.


Dirschl D, Hurwitz S, Brown TD, Nepola J. Tibial plafond fractures: A randomized trial of post-operative motion vs. non-motion. J. Orthop. Trauma. (Accepted)

Elkins JM, O’Brien MK, Stroud NJ, Pedersen DR, Callaghan JJ, Brown TD. Hard-on-hard total hip impingement causes extreme contact stress concentrations. Clin. Orthop. Relat. Res. 2011;469:454463.

Elkins JM, Stroud NJ, Rudert MJ, Tochigi Y, Pedersen DR, Ellis BJ, Callaghan JJ, Weiss JA, Brown TD. The capsule’s contribution to total hip construct stabilityA finite element analysis. J. Orthop. Res. William H. Harris Award Winner. J. Orthop. Res. 2011 Apr 14:1642-8. NIHMS287355.

Elkins JM, Pedersen DR, Callaghan JJ, Brown TD. Fracture propagation propensity of ceramic liners during impingement—A finite element exploration. J. Arthroplasty 2012 Apr;27(4):520-6. PMID 21855277.

Elkins JM, Kruger KM, Pedersen DR, Callaghan JJ, Brown TD. Edge-loading severity as a function of cup lip radius in metal-on-metal total hips—A finite element analysis. J. Orthop. Res. 2012;30(2):169-77. PMID 21812025.

Elkins JM, Liu X, Qin X, Du Z, Brown TD. Fracture modeling of ceramic liners for total hip arthroplasty. SIMULIA’s Realistic Simulation News. Sept/Oct 2011;p.21.

Elkins JM, Pedersen DR, Callaghan JJ, Brown TD.  Bone-on-bone versus hardware impingement in total hips:  A biomechanical study.  The Iowa Orthop. Journal. 2012 (Accepted)

Elkins JM, Pedersen DR, Callaghan JJ, Brown TD.  Do obesity and/or stripe wear increase ceramic liner fracture risk? An XFEM analysis. Clin. Orthop. Relat. Res. 2012 (Accepted)

Fakhry A, Tan SC, Heiner AD, Dehkordi-Vakil FH, Dircks WH. Methodology for measuring the in vitro seating and unseating forces of prefabricated attachment systems used to retain implant overdentures. J. Prosthodont.  2010;19(2):87–94.

Femino JE, Vaseenon T, Levin DA, Yian EH. Modification of the sinus tarsi approach for open reduction and plate fixation of intra-articular calcaneus fractures: the limits of proximal extension based upon the vascular anatomy of the lateral calcaneal artery. Iowa Orthop. J. 2010;30:161–167. PMC2958289

Goetz JE, Thedens DR, Kunze NM, Lawler EA, Brown TD. Day-to-day variability of median nerve location within the carpal tunnel. Clin. Biomech. 2010;25:660665. PMC2900433.

Goetz JE, Robinson DA, Pedersen DR, Conzemius MG, Brown TD. Cryoinsult parameter effects on the histologically-apparent volume of experimentally-induced osteonecrotic lesions. J. Orthop. Res. 2011;29(6):931–937. PMC3082588.

Goetz JE, Baer TE. Mechanical behavior of carpal tunnel subsynovial connective tissue under compression. Iowa Orthop. J. Iowa Orthop. J. 2011;31:127–132.

Goreham-Voss CM, Hyde PJ, Hall RM, Fisher J, Brown TD. Cross-shear implementation in sliding-distance-coupled finite element analysis of wear in metal-on-polyethylene total joint arthroplasty: Intervertebral total disc replacement as an illustrative application. J. Biomech. 2010;43(9):1674–1681. PMC2882534. 

Goreham-Voss CM, Vicars R, Hall RM, Brown TD. Preferential superior surface motion in wear simulations of the Charite total disc replacement. Eur. Spine J. 2010 Jun 26:1-9.

Heiner AD, Galvin AL, Fisher J, Callaghan JJ, Brown TD. Scratching vulnerability of conventional vs. highly crosslinked polyethylene liners due to large embedded third body particles. J. Arthroplasty. 2012;27(5);742-749. PMID: 22115764.

Heiner AD, Kruger KM, Baer TE, Brown TD. Enhancing damage visibility on metallic bearing surfaces: A simple technique for photography and viewing. J. Arthroplasty 2012 (Accepted)

Intema F, Thomas TP, Anderson DD, Elkins JM, Brown TD, Amendola A, Lafeber FPJG, Saltzman CL. Subchondral bone remodeling is related to clinical improvement after joint distraction in the treatment of ankle osteoarthritis. Osteoarthritis Cartilage. 2011;19(6):668–675. PMC3097273.

Kang L, Baer TE, Rudert MJ, Pedersen DR, Brown TD. Traveling-load calibration of grid-array transient contact stress sensors. J. Biomech. 2010;43:2237–2240. PMC2914204.

Kang L, Lewis ELV, Mohanraj J, Brown TD, Barton D, Jin ZM, Fisher J. The molecular orientation induced by multi-directional sliding in the UHMWPE used for the artificial joint replacements. Advanced Tribology. 2010, Part 3, V., 837–838.

Main EK, Goetz JE, Rudert MJ, Goreham-Voss CM, Brown TD. Apparent transverse compressive material properties of the digital flexor tendons and the median nerve in the carpal tunnel. J. Biomech. 2011;44:863–868. PMC3048925.

Main EK, Goetz JE, Baer TE, Klocke NF, Brown TD.  Volar/dorsal compressive mechanical behavior of the transverse carpal ligament.  J. Biomech. 2012;45(7);1180-1185. PMID: 22381735

Marsh JL, McKinley TO, Dirschl D, Pick A, Haft G, Anderson DD, Brown TD. The sequential recovery of health status after tibial plafond fractures. J. Orthop. Trauma. 2010;24(8):499–504.

Masrouha KZ, Anderson DD, Thomas TP, Kuhl LL, Brown TD, Marsh JL. Acute articular fracture severity and chronic cartilage stress challenge as quantitative risk factors for post-traumatic osteoarthritis: Illustrative cases. Iowa Orthop. J. 2010;30:47–54. PMC2958270.

Olson SA, Brown TD, Athanasiou KA, Dirschl DR: Applied biomechanics in articular injuries: Perspectives in basic investigation of articular injuries and clinical application. AAOS Instr. Course Lect. 2011;60:583–594.

Pedersen DR, Klocke NF, Thedens DR, Martin JA, Williams GN, Amendola A. Integrating cartilage-specific T1rho MRI into knee clinic diagnostic imaging. Iowa Orthop. J. 2011;31:99–109.

Ramakrishnan PS, Hecht BA, Pedersen DR, Lavery MR, Maynard J, Buckwalter JA, Martin JA. Oxidant conditioning protects cartilage from mechanically induced damage.  J. Orthop. Res. 2010 Jul;28(7):914920.

Ramakrishnan PS, Pedersen DR, Stroud NJ, McCabe DJ, Martin JA. Repeated measurement of mechanical properties in viable osteochondral explants following a single blunt impact injury. Proc. Inst. Mech. Eng. [H]. 2011 (In Press)

Rumery MP, Pedersen DR, Mendoza SA, Siepe C, Mayer HM, Brown TD. A pose-based image analysis technique for measuring in vivo wear of total disc replacements. Comput. Methods Biomech. Biomed. Engin. GCMB-2007-0059. (Accepted pending minor revision)

Saha PK, Xu Y, Duan H, Heiner AD, Liang G. Volumetric topological analysis: A novel approach for trabecular bone classification on the continuum between plates and rods. IEEE Transactions on Medical Imaging. 2010;29(11):1821–1838. PMC3113685.

Saltzman CL, Hillis SL, Stolley MP, Anderson DD, Amendola A. Prospective randomized controlled trial of motion vs. fixed distraction of ankle joint in the treatment of ankle osteoarthritis. J. Bone Joint Surg. [Am] (Provisionally Accepted).


Segal NA, Kern AM, Anderson DD, Niu J, Lynch JA, Guermazi A, Torner JC, Brown TD, Nevitt MC.  Elevated tibiofemoral articular contact stress predicts risk for bone marrow lesions and cartilage damage at 30 months.  Osteoarthritis Cartilage. (Accepted)


Shane E, Burr D, Ebeling PR, Abrahamsen B, Adler RA, Brown TD, Cheung AM, Cosman F, Curtis JR, Dell R, Dempster D, Einhorn TA, Genant HK, Geusens P, Klaushofer K, Koval K, Lane JM, McKiernan F, McKinney R, Ng A, Nieves J, O’Keefe R, Papapoulos S, Tet Sen H, van der Meulen MCH, Weinstein RS, Whyte M. Atypical subtrochanteric and diaphyseal femoral fractures: Report of a task force of the American Society for Bone and Mineral Research. J. Bone Miner. Res. 2010;25(11):1–28.


Thomas TP, Anderson DD, Mosqueda TV, Van Hofwegen CJ, Hillis SL, Marsh JL, Brown TD. Objective CT-based metrics of articular fracture severity to assess risk for post-traumatic osteoarthritis. J. Orthop. Trauma.


Thomas TP, Anderson DD, Willis AR, Lui P, Frank MC, Marsh JL, Brown TD. A computational/experimental platform for investigating three-dimensional puzzle solving of comminuted articular fractures. Comput. Methods Biomech. Biomed. Engin. 2011;14(3):263270. PMC3045471.

Thomas TP, Anderson DD, Willis AR, Liu P, Marsh JL, Brown TD. ASB clinical biomechanics award paper 2010: Virtual pre-operative reconstruction planning for comminuted articular fractures. Clin. Biomech. 2011;26(2):109–115.  PMC3034816.

Tochigi Y, Segal NA, Vaseenon T, Brown TD.  Entropy analysis of tri-axial leg acceleration signal waveforms for measurement of decrease of physiological variability in human gait.  J. Orthop. Res. 2012;30(6);897-904. PMID: 22144127

Tochigi Y, Vaseenon T, Heiner AD, Fredericks DC, Martin JA, Rudert MJ, Hillis SL, Brown TD, McKinley TO. Instability dependency of OA development in a rabbit model of graded ACL transection. J. Bone Joint Surg. 2011;93(7):640–647. PMC3064002.

Tochigi Y, Buckwalter JA, Martin JA, Hillis SL, Zhang P, Vaseenon T, Lehman AD, Brown TD. Distribution and progression of chondrocyte damage in a whole-organ model of human ankle intra-articular fracture. J. Bone Joint Surg. Am. 2011;93(6):533–539. PMC3052703.

Vaseenon T, Phisitkul P. A novel tendinous interconnection release technique for claw-toe deformity. Iowa Orthop. J. 2010;30:157–160. PMC2958288.


Vaseenon T, Tochigi Y, Heiner AD, Goetz JE, Baer TE, Fredericks DC, Martin JA, Rudert MJ, Hillis SL, Brown TD, McKinley TO. Organ-level histological and biomechanical responses from localized incongruity in the rabbit knee.

J. Orthop. Res. 2011 Mar;29(3):340–346.


Yin Y, Zhang X, Williams R, Wu X, Anderson DD, Sonka M. LOGISMOS — Layered optimal graph image segmentation of multiple objects and surfaces: Cartilage segmentation in the knee joint. IEEE Transactions on Medical Imaging. 2010;29(12):2023-2037. PMC3131162.

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